Abrogation of RUNX1 gene expression in de novo myelodysplastic syndrome with t(4;21)(q21;q22)

The disruption of RUNX1 function is one of the main mechanisms of disease observed in hematopoietic malignancies and the description of novel genetic events that lead to a RUNX1 loss of function has been accelerated with the development of genomic technologies. Here we describe the molecular charact...

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Detalhes bibliográficos
Main Authors: Rio-Machín, Ana, Menezes, Juliane, Maiques-Diaz, Alba, Agirre, Xabier, Ferreira, Bibiana I., Acquadro, Francesco, Rodriguez-Perales, Sandra, Juaristi, Karmele A., Álvarez, Sara, Cigudosa, Juan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2012
Assuntos:
Original Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347656/
https://ncbi.nlm.nih.gov/pubmed/22102704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.050567
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