Decrease in JAK2(V617F) allele burden is not a prerequisite to clinical response in patients with polycythemia vera

BACKGROUND: Although reduction in the JAK2(V617F) allele burden (%V617F) has been suggested as a criterion for defining disease response to cytoreductive therapy in polycythemia vera, its value as a response monitor is unclear. The purpose of this study is to determine whether a reduction in %V617F...

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Главные авторы: Kuriakose, Emil, Vandris, Katherine, Wang, Y. Lynn, Chow, William, Jones, Amy V., Christos, Paul, Cross, Nicholas C.P., Silver, Richard T.
Формат: Artigo
Язык:Inglês
Опубликовано: Ferrata Storti Foundation 2012
Предметы:
Original Articles and Brief Reports
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347655/
https://ncbi.nlm.nih.gov/pubmed/22102708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.053348
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