JAK2(V617F) allele burden in polycythemia vera correlates with grade of myelofibrosis, but is not substantially affected by therapy

In a series of 105 patients with polycythemia vera, we retrospectively determined whether the JAK2(V617F) mutation correlated with severity of disease phenotype. Higher JAK2(V617F) allele burden correlated with more advanced myelofibrosis, greater splenomegaly, and higher white blood cell count, but...

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Bibliografische gegevens
Hoofdauteurs: Silver, Richard T., Vandris, Katherine, Wang, Y. Lynn, Adriano, Fernando, Jones, Amy V., Christos, Paul J., Cross, Nicholas C.P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626091/
https://ncbi.nlm.nih.gov/pubmed/20650526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2010.06.017
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