Deamination of 5-Methylcytosine Residues in Mammalian Cells

DNA demethylation in mammalia occurs after fertilization and during embryogenesis and accompanies cell aging and cancer transformation. With the help of the primer extension reaction, MALDI MS and DNA cleavage by thymine DNA glycosylase deamination of 5-methylcytosine residues has been shown to take...

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Autors principals: Gromenko, E.V., Spirin, P.V., Kubareva, E.A., Romanova, E.A., Prassolov, V.S., Shpanchenko, O.V., Dontsova, O.A.
Format: Artigo
Idioma:Inglês
Publicat: A.I. Gordeyev 2009
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347525/
https://ncbi.nlm.nih.gov/pubmed/22649624
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