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Deamination of 5-Methylcytosine Residues in Mammalian Cells

DNA demethylation in mammalia occurs after fertilization and during embryogenesis and accompanies cell aging and cancer transformation. With the help of the primer extension reaction, MALDI MS and DNA cleavage by thymine DNA glycosylase deamination of 5-methylcytosine residues has been shown to take...

詳細記述

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書誌詳細
主要な著者: Gromenko, E.V., Spirin, P.V., Kubareva, E.A., Romanova, E.A., Prassolov, V.S., Shpanchenko, O.V., Dontsova, O.A.
フォーマット: Artigo
言語:Inglês
出版事項: A.I. Gordeyev 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347525/
https://ncbi.nlm.nih.gov/pubmed/22649624
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