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Scd1 Plays a Tumor-Suppressive Role in Survival of Leukemia Stem Cells and the Development of Chronic Myeloid Leukemia

Chronic myeloid leukemia (CML) is derived from a stem cell, and it is widely accepted that the existence of leukemia stem cells (LSCs) is one of the major reasons for the relapse of CML treated with kinase inhibitors. Key to eradicating LSCs is to identify genes that play a critical role in survival...

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Détails bibliographiques
Auteurs principaux: Zhang, Haojian, Li, Huawei, Ho, Ngoc, Li, Dongguang, Li, Shaoguang
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347408/
https://ncbi.nlm.nih.gov/pubmed/22431519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05672-11
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