Live-Cell Imaging Reveals Multiple Interactions between Epstein-Barr Virus Nuclear Antigen 1 and Cellular Chromatin during Interphase and Mitosis

Epstein-Barr virus (EBV) establishes a life-long latent infection in humans. In proliferating latently infected cells, EBV genomes persist as multiple episomes that undergo one DNA replication event per cell cycle and remain attached to the mitotic chromosomes. EBV nuclear antigen 1 (EBNA-1) binding...

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Detalhes bibliográficos
Main Authors: Jourdan, Nathalie, Jobart-Malfait, Aude, Dos Reis, Gabriel, Quignon, Frédérique, Piolot, Tristan, Klein, Christophe, Tramier, Marc, Coppey-Moisan, Maïté, Marechal, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347338/
https://ncbi.nlm.nih.gov/pubmed/22345443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06303-11
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