Modified Vaccinia Virus Ankara-Based Vaccine Vectors Induce Apoptosis in Dendritic Cells Draining from the Skin via both the Extrinsic and Intrinsic Caspase Pathways, Preventing Efficient Antigen Presentation

Dendritic cells (DC) are potent antigen-presenting cells and central to the induction of immune responses following infection or vaccination. The collection of DC migrating from peripheral tissues by cannulation of the afferent lymphatic vessels provides DC which can be used directly ex vivo without...

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Main Authors: Guzman, E., Cubillos-Zapata, C., Cottingham, M. G., Gilbert, S. C., Prentice, H., Charleston, B., Hope, J. C.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2012
נושאים:
Vaccines and Antiviral Agents
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347273/
https://ncbi.nlm.nih.gov/pubmed/22419811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00264-12
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