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Newcastle Disease Virus Exerts Oncolysis by both Intrinsic and Extrinsic Caspase-Dependent Pathways of Cell Death

Newcastle disease virus (NDV), an avian paramyxovirus, is tumor selective and intrinsically oncolytic. Here, we present evidence that genetically modified, recombinant NDV strains are cytotoxic to human tumor cell lines of ecto-, endo-, and mesodermal origin. We show that cytotoxicity against tumor...

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Bibliografische gegevens
Hoofdauteurs: Elankumaran, Subbiah, Rockemann, Daniel, Samal, Siba K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2006
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563725/
https://ncbi.nlm.nih.gov/pubmed/16840332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00241-06
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