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Structure of the Fab-Labeled “Breathing” State of Native Poliovirus

At 37°C, the structure of poliovirus is dynamic, and internal polypeptides VP4 and N terminus of VP1 (residues 1 to 53) externalize reversibly. An Fab fragment of a monospecific antibody, which binds to residues 39 to 55 of VP1, was utilized to locate the N termini of VP1 in native (160S) particles...

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Detaylı Bibliyografya
Asıl Yazarlar: Lin, Jun, Lee, Lily Y., Roivainen, Merja, Filman, David J., Hogle, James M., Belnap, David M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347258/
https://ncbi.nlm.nih.gov/pubmed/22398295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05990-11
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