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Structure of the Fab-Labeled “Breathing” State of Native Poliovirus
At 37°C, the structure of poliovirus is dynamic, and internal polypeptides VP4 and N terminus of VP1 (residues 1 to 53) externalize reversibly. An Fab fragment of a monospecific antibody, which binds to residues 39 to 55 of VP1, was utilized to locate the N termini of VP1 in native (160S) particles...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3347258/ https://ncbi.nlm.nih.gov/pubmed/22398295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05990-11 |
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