A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ

Through functional expression screening, we identified a gene, designated Humanin (HN) cDNA, which encodes a short polypeptide and abolishes death of neuronal cells caused by multiple different types of familial Alzheimer's disease genes and by Aβ amyloid, without effect on death by Q79 or supe...

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Autori principali: Hashimoto, Yuichi, Niikura, Takako, Tajima, Hirohisa, Yasukawa, Takashi, Sudo, Haruka, Ito, Yuko, Kita, Yoshiko, Kawasumi, Masaoki, Kouyama, Keisuke, Doyu, Manabu, Sobue, Gen, Koide, Takashi, Tsuji, Shoji, Lang, Jochen, Kurokawa, Kiyoshi, Nishimoto, Ikuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2001
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC33469/
https://ncbi.nlm.nih.gov/pubmed/11371646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.101133498
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