Pulmonary Disposition of Tedizolid following Administration of Once-Daily Oral 200-Milligram Tedizolid Phosphate in Healthy Adult Volunteers

This study assessed the pulmonary disposition of tedizolid, an oxazolidinone, in adult volunteers receiving 200 mg of the prodrug tedizolid phosphate orally every 24 h for 3 days to steady state. Plasma samples were collected over the dosing interval, and participants were randomized to undergo bron...

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Bibliographic Details
Main Authors: Housman, Seth T., Pope, J. Samuel, Russomanno, John, Salerno, Edward, Shore, Eric, Kuti, Joseph L., Nicolau, David P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346604/
https://ncbi.nlm.nih.gov/pubmed/22330925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05354-11
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