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Bronchopulmonary Disposition of Micafungin in Healthy Adult Volunteers

By way of bronchoscopy and bronchoalveolar lavage, intrapulmonary steady-state concentrations of micafungin administered at 150 mg daily to 15 healthy volunteers were determined at 4, 12, and 24 h after the third dose. The micafungin disposition was predominantly intracellular, with approximately 10...

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Détails bibliographiques
Auteurs principaux: Nicasio, Anthony M., Tessier, Pamela R., Nicolau, David P., Knauft, R. Fredrick, Russomanno, John, Shore, Eric, Kuti, Joseph L.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650581/
https://ncbi.nlm.nih.gov/pubmed/19114675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01386-08
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