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Persistent Sonic hedgehog Signaling in Adult Brain Determines Neural Stem Cell Positional Identity
Neural Stem Cells (NSCs) persist in the subventricular zone (SVZ) of the adult brain. Location within this germinal region determines the type of neuronal progeny NSCs generate, but the mechanism of adult NSC positional specification remains unknown. We show that sonic hedgehog (Shh) signaling, resu...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3346180/ https://ncbi.nlm.nih.gov/pubmed/21791285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.05.018 |
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