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Sonic Hedgehog Expression in Corticofugal Projection Neurons Directs Cortical Microcircuit Formation

The precise connectivity of inputs and outputs is critical for cerebral cortex function; however, the cellular mechanisms that establish these connections are poorly understood. Here, we show that the secreted molecule Sonic Hedgehog (Shh) is involved in synapse formation of a specific cortical circ...

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Detalhes bibliográficos
Main Authors: Harwell, Corey C., Parker, Philip R.L., Gee, Steven M., Okada, Ami, McConnell, Susan K., Kreitzer, Anatol C., Kriegstein, Arnold R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551478/
https://ncbi.nlm.nih.gov/pubmed/22445340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.02.009
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