Protein-tyrosine Phosphatase 1B (PTP1B) Deficiency Confers Resistance to Transforming Growth Factor-β (TGF-β)-induced Suppressor Effects in Hepatocytes

Transforming growth factor-β (TGF-β) plays a dual role in hepatocytes, mediating both tumor suppressor and promoter effects. The suppressor effects of the cytokine can be negatively regulated by activation of survival signals, mostly dependent on tyrosine kinase activity. The aim of our work was to...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Ortiz, Conrad, Caja, Laia, Bertran, Esther, Gonzalez-Rodriguez, Águeda, Valverde, Ángela M., Fabregat, Isabel, Sancho, Patricia
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346142/
https://ncbi.nlm.nih.gov/pubmed/22427664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.303958
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker