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S100P Dissociates Myosin IIA Filaments and Focal Adhesion Sites to Reduce Cell Adhesion and Enhance Cell Migration

S100 proteins promote cancer cell migration and metastasis. To investigate their roles in the process of migration we have constructed inducible systems for S100P in rat mammary and human HeLa cells that show a linear relationship between its intracellular levels and cell migration. S100P, like S100...

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Detalhes bibliográficos
Main Authors: Du, Min, Wang, Guozheng, Ismail, Thamir M., Gross, Stephane, Fernig, David G., Barraclough, Roger, Rudland, Philip S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346139/
https://ncbi.nlm.nih.gov/pubmed/22399300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.349787
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