Mechanistic Studies on Activation of Ubiquitin and Di-ubiquitin-like Protein, FAT10, by Ubiquitin-like Modifier Activating Enzyme 6, Uba6

Uba6 is a homolog of the ubiquitin-activating enzyme, Uba1, and activates two ubiquitin-like proteins (UBLs), ubiquitin and FAT10. In this study, biochemical and biophysical experiments were performed to understand the mechanisms of how Uba6 recognizes two distinct UBLs and catalyzes their activatio...

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Hlavní autoři: Gavin, James M., Chen, Jesse J., Liao, Hua, Rollins, Neil, Yang, Xiaofeng, Xu, Qing, Ma, Jingya, Loke, Huay-Keng, Lingaraj, Trupti, Brownell, James E., Mallender, William D., Gould, Alexandra E., Amidon, Benjamin S., Dick, Lawrence R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Enzymology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346097/
https://ncbi.nlm.nih.gov/pubmed/22427669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.336198
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