Matrix Metalloproteinase-10 (MMP-10) Interaction with Tissue Inhibitors of Metalloproteinases TIMP-1 and TIMP-2: BINDING STUDIES AND CRYSTAL STRUCTURE

Matrix metalloproteinase 10 (MMP-10, stromelysin-2) is a secreted metalloproteinase with functions in skeletal development, wound healing, and vascular remodeling; its overexpression is also implicated in lung tumorigenesis and tumor progression. To understand the regulation of MMP-10 by tissue inhi...

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Main Authors: Batra, Jyotica, Robinson, Jessica, Soares, Alexei S., Fields, Alan P., Radisky, Derek C., Radisky, Evette S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Protein Structure and Folding
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346077/
https://ncbi.nlm.nih.gov/pubmed/22427646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.341156
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