Directing Integrin-linked Endocytosis of Recombinant AAV Enhances Productive FAK-dependent Transduction

Recombinant adeno-associated virus (rAAV) is a widely used gene therapy vector. Although a wide range of rAAV serotypes can effectively enter most cell types, their transduction efficiencies (i.e., transgene expression) can vary widely depending on the target cell type. Integrins play important role...

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Bibliografiske detaljer
Main Authors: Kaminsky, Paul M, Keiser, Nicholas W, Yan, Ziying, Lei-Butters, Diana CM, Engelhardt, John F
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345987/
https://ncbi.nlm.nih.gov/pubmed/22233580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.295
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