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Directing Integrin-linked Endocytosis of Recombinant AAV Enhances Productive FAK-dependent Transduction

Recombinant adeno-associated virus (rAAV) is a widely used gene therapy vector. Although a wide range of rAAV serotypes can effectively enter most cell types, their transduction efficiencies (i.e., transgene expression) can vary widely depending on the target cell type. Integrins play important role...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kaminsky, Paul M, Keiser, Nicholas W, Yan, Ziying, Lei-Butters, Diana CM, Engelhardt, John F
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345987/
https://ncbi.nlm.nih.gov/pubmed/22233580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.295
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