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Why rethink the structure-function relationships regulating TCR behavior?

Although the generally accepted (Standard) Model of the TCR has powered the accumulation of a large body of crucial data, it is lacking because of the failure of its basic tenet that allele-specific recognition of MHC-encoded restricting elements can be derived by somatic selection on a random reper...

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Autor principal: Cohn, Melvin
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345953/
https://ncbi.nlm.nih.gov/pubmed/22573930
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