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An in depth analysis of the concept of “polyspecificity” assumed to characterize TCR/BCR recognition

A workshop group developed the concept of a “polyspecific” TCR/BCR in the framework of today’s consensus model. They argue that the individual TCR/BCR combining site is composed of a packet of specificities randomly plucked from the repertoire, hence it is “polyspecific.” This essay analyzes the con...

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Detalhes bibliográficos
Autor principal: Cohn, Melvin
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892925/
https://ncbi.nlm.nih.gov/pubmed/18213526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-007-8003-z
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