pH as a biomarker of neurodegeneration in Huntington's disease: a translational rodent-human MRS study

Early diagnosis and follow-up of neurodegenerative diseases are often hampered by the lack of reliable biomarkers. Neuroimaging techniques like magnetic resonance spectroscopy (MRS) offer promising tools to detect biochemical alterations at early stages of degeneration. Intracellular pH, which can b...

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Главные авторы: Chaumeil, Myriam M, Valette, Julien, Baligand, Céline, Brouillet, Emmanuel, Hantraye, Philippe, Bloch, Gilles, Gaura, Véronique, Rialland, Amandine, Krystkowiak, Pierre, Verny, Christophe, Damier, Philippe, Remy, Philippe, Bachoud-Levi, Anne-Catherine, Carlier, Pierre, Lebon, Vincent
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2012
Предметы:
Feature Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345921/
https://ncbi.nlm.nih.gov/pubmed/22373643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.15
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