pH as a biomarker of neurodegeneration in Huntington's disease: a translational rodent-human MRS study

Early diagnosis and follow-up of neurodegenerative diseases are often hampered by the lack of reliable biomarkers. Neuroimaging techniques like magnetic resonance spectroscopy (MRS) offer promising tools to detect biochemical alterations at early stages of degeneration. Intracellular pH, which can b...

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Détails bibliographiques
Auteurs principaux: Chaumeil, Myriam M, Valette, Julien, Baligand, Céline, Brouillet, Emmanuel, Hantraye, Philippe, Bloch, Gilles, Gaura, Véronique, Rialland, Amandine, Krystkowiak, Pierre, Verny, Christophe, Damier, Philippe, Remy, Philippe, Bachoud-Levi, Anne-Catherine, Carlier, Pierre, Lebon, Vincent
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2012
Sujets:
Feature Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345921/
https://ncbi.nlm.nih.gov/pubmed/22373643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.15
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