pH as a biomarker of neurodegeneration in Huntington's disease: a translational rodent-human MRS study

Early diagnosis and follow-up of neurodegenerative diseases are often hampered by the lack of reliable biomarkers. Neuroimaging techniques like magnetic resonance spectroscopy (MRS) offer promising tools to detect biochemical alterations at early stages of degeneration. Intracellular pH, which can b...

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Detalhes bibliográficos
Main Authors: Chaumeil, Myriam M, Valette, Julien, Baligand, Céline, Brouillet, Emmanuel, Hantraye, Philippe, Bloch, Gilles, Gaura, Véronique, Rialland, Amandine, Krystkowiak, Pierre, Verny, Christophe, Damier, Philippe, Remy, Philippe, Bachoud-Levi, Anne-Catherine, Carlier, Pierre, Lebon, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Feature Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345921/
https://ncbi.nlm.nih.gov/pubmed/22373643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.15
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