Fidelity of replication of the leading and the lagging DNA strands opposite N-methyl-N-nitrosourea-induced DNA damage in human cells.

Semi-conservative replication of double-stranded DNA in eukaryotic cells is an asymmetric process involving leading and lagging strand synthesis and different DNA polymerases. We report a study to analyze the effect of these asymmetries when the replication machinery encounters alkylation-induced DN...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Basic-Zaninovic, T, Palombo, F, Bignami, M, Dogliotti, E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1992
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334569/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1336179/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.24.6543
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