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Palmitoylation by DHHC5/8 targets GRIP1 to dendritic endosomes to regulate AMPA-R trafficking
Palmitoylation, a key regulatory mechanism controlling protein targeting, is catalyzed by DHHC-family palmitoyl acyltransferases (PATs). Impaired PAT activity is linked to several neurodevelopmental and neuropsychiatric disorders, suggesting critical roles for palmitoylation in neuronal function. Ho...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3345505/ https://ncbi.nlm.nih.gov/pubmed/22325201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.11.021 |
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