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Combination Therapy Using tPA and Edaravone Improves the Neurotoxic Effect of tPA

In acute ischemic stroke patients, administration of tissue plasminogen activator (tPA) was proven to improve clinical outcome. On the other hand, neurotoxic effects of tPA have been reported in animal experimental studies. Using a rat thromboembolic stroke model, we examined whether or not the free...

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Autors principals: Kano, T., Harada, T., Hirayama, T., Katayama, Y.
Format: Artigo
Idioma:Inglês
Publicat: Centauro S.r.l. 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345452/
https://ncbi.nlm.nih.gov/pubmed/20566086
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