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Inhibition of hepatic Sulf2 in vivo: a novel strategy to correct diabetic dyslipidemia
BACKGROUND: Type 2 diabetes mellitus (T2DM) impairs hepatic clearance of atherogenic postprandial triglyceride-rich lipoproteins (TRL). We recently reported that livers from T2DM db/db mice markedly overexpress glucosamine-6-O-endosulfatase-2 (SULF2), an enzyme that removes 6-O sulfate groups from h...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3345297/ https://ncbi.nlm.nih.gov/pubmed/22234891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25580 |
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