Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma

The abscopal effect is a phenomenon in which local radiotherapy is associated with the regression of metastatic cancer at a distance from the irradiated site. The abscopal effect may be mediated by activation of the immune system. Ipilimumab is a monoclonal antibody that inhibits an immunologic chec...

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Hauptverfasser: Postow, Michael A., Callahan, Margaret K., Barker, Christopher A., Yamada, Yoshiya, Yuan, Jianda, Kitano, Shigehisa, Mu, Zhenyu, Rasalan, Teresa, Adamow, Matthew, Ritter, Erika, Sedrak, Christine, Jungbluth, Achim A., Chua, Ramon, Yang, Arvin S., Roman, Ruth-Ann, Rosner, Samuel, Benson, Brenna, Allison, James P., Lesokhin, Alexander M., Gnjatic, Sacha, Wolchok, Jedd D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345206/
https://ncbi.nlm.nih.gov/pubmed/22397654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1112824
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