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A phosphorothioate at the 3' splice-site inhibits the second splicing step in a group I intron.

RNA polymerases can synthesize RNA containing phosphorothioate linkages in which a sulfur replaces one of the nonbridging oxygens. Only the Rp isomer is generated during transcription. A Rp phosphorothioate at the 5' splice-site of the Tetrahymena group I intron does not inhibit splicing (McSwi...

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Bibliografiske detaljer
Main Authors: Suh, E, Waring, R B
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC334520/
https://ncbi.nlm.nih.gov/pubmed/1282238
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