A phosphorothioate at the 3' splice-site inhibits the second splicing step in a group I intron.
RNA polymerases can synthesize RNA containing phosphorothioate linkages in which a sulfur replaces one of the nonbridging oxygens. Only the Rp isomer is generated during transcription. A Rp phosphorothioate at the 5' splice-site of the Tetrahymena group I intron does not inhibit splicing (McSwiggen,...
Na minha lista:
| Udgivet i: | Nucleic Acids Res |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1992
|
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC334520/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1282238/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.23.6303 |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|