The conserved U.G pair in the 5' splice site duplex of a group I intron is required in the first but not the second step of self-splicing.
Group I self-splicing introns have a 5' splice site duplex (P1) that contains a single conserved base pair (U.G). The U is the last nucleotide of the 5' exon, and the G is part of the internal guide sequence within the intron. Using site-specific mutagenesis and analysis of the rate and accuracy of...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362426/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2779562/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.9.3657-3666.1989 |
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