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The conserved U.G pair in the 5' splice site duplex of a group I intron is required in the first but not the second step of self-splicing.

Group I self-splicing introns have a 5' splice site duplex (P1) that contains a single conserved base pair (U.G). The U is the last nucleotide of the 5' exon, and the G is part of the internal guide sequence within the intron. Using site-specific mutagenesis and analysis of the rate and accuracy of...

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Publicado en:Mol Cell Biol
Autores principales: Barfod, E T, Cech, T R
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 1989
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362426/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2779562/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.9.3657-3666.1989
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