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Immunogenicity and cross-reactivity of a representative ancestral sequence in HCV infection()
Vaccines designed to prevent or to treat hepatitis C viral infection must achieve maximum cross reactivity against widely divergent circulating strains. Rational approaches for sequence selection to maximize immunogenicity and minimize genetic distance across circulating strains may enhance vaccine...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3345099/ https://ncbi.nlm.nih.gov/pubmed/22508927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103008 |
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