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Regulated pre-mRNA splicing: the ghostwriter of the eukaryotic genome

Intron removal is at the heart of mRNA synthesis. It is mediated by one of the cell's largest complexes, the spliceosome. Yet, the fundamental chemistry involved is simple. In this review we will address how the spliceosome acts in diverse ways to optimize gene expression in order to meet the c...

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Bibliografische gegevens
Hoofdauteurs: Johnson, Tracy L., Vilardell, Josep
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345063/
https://ncbi.nlm.nih.gov/pubmed/22248620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2011.12.011
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