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Co-Evolution of Primate SAMHD1 and Lentivirus Vpx Leads to the Loss of the vpx Gene in HIV-1 Ancestor

Cross-species transmission and adaptation of simian immunodeficiency viruses (SIVs) to humans have given rise to human immunodeficiency viruses (HIVs). HIV type 1 (HIV-1) and type 2 (HIV-2) were derived from SIVs that infected chimpanzee (SIVcpz) and sooty mangabey (SIVsm), respectively. The HIV-1 r...

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Detalhes bibliográficos
Main Authors: Zhang, Chiyu, de Silva, Suresh, Wang, Jian-Hua, Wu, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345027/
https://ncbi.nlm.nih.gov/pubmed/22574228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037477
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