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β-Catenin signaling initiates the activation of astrocytes and its dysregulation contributes to the pathogenesis of astrocytomas

Astrocytes are the most abundant cell of the CNS and demonstrate contact inhibition in which a nonproliferative, nonmotile cellular state is achieved once stable intercellular contacts are formed between mature cells. Cellular injury disrupts these intercellular contacts, causing a loss of contact i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yang, Chunzhang, Iyer, Rajiv R., Yu, Albert C. H., Yong, Raymund L., Park, Deric M., Weil, Robert J., Ikejiri, Barbara, Brady, Roscoe O., Lonser, Russell R., Zhuang, Zhengping
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344971/
https://ncbi.nlm.nih.gov/pubmed/22505738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118754109
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