β-Catenin signaling initiates the activation of astrocytes and its dysregulation contributes to the pathogenesis of astrocytomas

Astrocytes are the most abundant cell of the CNS and demonstrate contact inhibition in which a nonproliferative, nonmotile cellular state is achieved once stable intercellular contacts are formed between mature cells. Cellular injury disrupts these intercellular contacts, causing a loss of contact i...

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Bibliographic Details
Main Authors: Yang, Chunzhang, Iyer, Rajiv R., Yu, Albert C. H., Yong, Raymund L., Park, Deric M., Weil, Robert J., Ikejiri, Barbara, Brady, Roscoe O., Lonser, Russell R., Zhuang, Zhengping
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344971/
https://ncbi.nlm.nih.gov/pubmed/22505738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118754109
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