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β-Catenin signaling initiates the activation of astrocytes and its dysregulation contributes to the pathogenesis of astrocytomas

Astrocytes are the most abundant cell of the CNS and demonstrate contact inhibition in which a nonproliferative, nonmotile cellular state is achieved once stable intercellular contacts are formed between mature cells. Cellular injury disrupts these intercellular contacts, causing a loss of contact i...

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Detalhes bibliográficos
Main Authors: Yang, Chunzhang, Iyer, Rajiv R., Yu, Albert C. H., Yong, Raymund L., Park, Deric M., Weil, Robert J., Ikejiri, Barbara, Brady, Roscoe O., Lonser, Russell R., Zhuang, Zhengping
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344971/
https://ncbi.nlm.nih.gov/pubmed/22505738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118754109
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