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Intrinsic disorder modulates protein self-assembly and aggregation

Protein molecules have evolved to adopt distinctive and well-defined functional and soluble states under physiological conditions. In some circumstances, however, proteins can self-assemble into fibrillar aggregates designated as amyloid fibrils. In vivo these processes are normally associated with...

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Hlavní autoři: De Simone, Alfonso, Kitchen, Craig, Kwan, Ann H., Sunde, Margaret, Dobson, Christopher M., Frenkel, Daan
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344965/
https://ncbi.nlm.nih.gov/pubmed/22509003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118048109
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