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Intrinsic disorder modulates protein self-assembly and aggregation
Protein molecules have evolved to adopt distinctive and well-defined functional and soluble states under physiological conditions. In some circumstances, however, proteins can self-assemble into fibrillar aggregates designated as amyloid fibrils. In vivo these processes are normally associated with...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3344965/ https://ncbi.nlm.nih.gov/pubmed/22509003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118048109 |
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