Allosteric modulation of nucleoporin assemblies by intrinsically disordered regions

Intrinsically disordered regions (IDRs) of proteins are implicated in key macromolecular interactions. However, the molecular forces underlying IDR function within multicomponent assemblies remain elusive. By combining thermodynamic and structural data, we have discovered an allostery-based mechanis...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Adv
Egile Nagusiak: Blus, Bartlomiej Jan, Koh, Junseock, Krolak, Aleksandra, Seo, Hyuk-Soo, Coutavas, Elias, Blobel, Günter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Association for the Advancement of Science 2019
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881172/
https://ncbi.nlm.nih.gov/pubmed/31807700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax1836
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