Interference with Oligomerization and Glycosaminoglycan Binding of the Chemokine CCL5 Improves Experimental Liver Injury

BACKGROUND: The chemokine CCL5 is involved in the recruitment of immune cells and a subsequent activation of hepatic stellate cells (HSC) after liver injury. We here investigate whether inhibition of CCL5 oligomerization and glycosaminoglycan binding by a mutated CCL5 protein ((44)AANA(47)-CCL5) has...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nellen, Andreas, Heinrichs, Daniel, Berres, Marie-Luise, Sahin, Hacer, Schmitz, Petra, Proudfoot, Amanda E., Trautwein, Christian, Wasmuth, Hermann E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344902/
https://ncbi.nlm.nih.gov/pubmed/22574195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036614
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak