Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice

Activation of hepatic stellate cells in response to chronic inflammation represents a crucial step in the development of liver fibrosis. However, the molecules involved in the interaction between immune cells and stellate cells remain obscure. Herein, we identify the chemokine CCL5 (also known as RA...

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Detalhes bibliográficos
Main Authors: Berres, Marie-Luise, Koenen, Rory R., Rueland, Anna, Zaldivar, Mirko Moreno, Heinrichs, Daniel, Sahin, Hacer, Schmitz, Petra, Streetz, Konrad L., Berg, Thomas, Gassler, Nikolaus, Weiskirchen, Ralf, Proudfoot, Amanda, Weber, Christian, Trautwein, Christian, Wasmuth, Hermann E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964968/
https://ncbi.nlm.nih.gov/pubmed/20978355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41732
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