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Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice

Activation of hepatic stellate cells in response to chronic inflammation represents a crucial step in the development of liver fibrosis. However, the molecules involved in the interaction between immune cells and stellate cells remain obscure. Herein, we identify the chemokine CCL5 (also known as RA...

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Main Authors: Berres, Marie-Luise, Koenen, Rory R., Rueland, Anna, Zaldivar, Mirko Moreno, Heinrichs, Daniel, Sahin, Hacer, Schmitz, Petra, Streetz, Konrad L., Berg, Thomas, Gassler, Nikolaus, Weiskirchen, Ralf, Proudfoot, Amanda, Weber, Christian, Trautwein, Christian, Wasmuth, Hermann E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964968/
https://ncbi.nlm.nih.gov/pubmed/20978355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41732
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