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Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase

Salmonella typhimurium DCyD (StDCyD) is a fold type II pyridoxal 5′ phosphate (PLP)-dependent enzyme that catalyzes the degradation of D-Cys to H(2)S and pyruvate. It also efficiently degrades β-chloro-D-alanine (βCDA). D-Ser is a poor substrate while the enzyme is inactive with respect to L-Ser and...

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Détails bibliographiques
Auteurs principaux: Bharath, Sakshibeedu R., Bisht, Shveta, Harijan, Rajesh K., Savithri, Handanahal S., Murthy, Mathur R. N.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344862/
https://ncbi.nlm.nih.gov/pubmed/22574144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036267
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