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Structural and mechanistic investigations on Salmonella typhimurium acetate kinase (AckA): identification of a putative ligand binding pocket at the dimeric interface

BACKGROUND: Bacteria such as Escherichia coli and Salmonella typhimurium can utilize acetate as the sole source of carbon and energy. Acetate kinase (AckA) and phosphotransacetylase (Pta), key enzymes of acetate utilization pathway, regulate flux of metabolites in glycolysis, gluconeogenesis, TCA cy...

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Hlavní autoři: Chittori, Sagar, Savithri, Handanahal S, Murthy, Mathur RN
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475010/
https://ncbi.nlm.nih.gov/pubmed/23031654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-12-24
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