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Structural and mechanistic investigations on Salmonella typhimurium acetate kinase (AckA): identification of a putative ligand binding pocket at the dimeric interface

BACKGROUND: Bacteria such as Escherichia coli and Salmonella typhimurium can utilize acetate as the sole source of carbon and energy. Acetate kinase (AckA) and phosphotransacetylase (Pta), key enzymes of acetate utilization pathway, regulate flux of metabolites in glycolysis, gluconeogenesis, TCA cy...

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書目詳細資料
Main Authors: Chittori, Sagar, Savithri, Handanahal S, Murthy, Mathur RN
格式: Artigo
語言:Inglês
出版: BioMed Central 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475010/
https://ncbi.nlm.nih.gov/pubmed/23031654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-12-24
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