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Identification and Characterization of Antifungal Compounds Using a Saccharomyces cerevisiae Reporter Bioassay

New antifungal drugs are urgently needed due to the currently limited selection, the emergence of drug resistance, and the toxicity of several commonly used drugs. To identify drug leads, we screened small molecules using a Saccharomyces cerevisiae reporter bioassay in which S. cerevisiae heterologo...

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Detalhes bibliográficos
Main Authors: Tebbets, Brad, Stewart, Douglas, Lawry, Stephanie, Nett, Jeniel, Nantel, Andre, Andes, David, Klein, Bruce S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344848/
https://ncbi.nlm.nih.gov/pubmed/22574132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036021
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